Every parent or spouse can relate to the loss of either a child or a spouse, even if they have never experienced it. I bet we would all say, “Take Me Instead.” I bet we would all be willing to make the sacrifice.
For God so loved the world, that he gave his only begotten Son, that whosoever believeth in him should not perish, but have everlasting life. For God sent not his Son into the world to condemn the world; but that the world through him might be saved. He that believeth on him is not condemned: but he that believeth not is condemned already, because he hath not believed in the name of the only begotten Son of God. (John3:16‑18)
For even the Son of man came not to be ministered unto, but to minister, and to give his life a ransom for many. (Mark 10:45)
How much more shall the blood of Christ, who through the eternal Spirit offered himself without spot to God, · · · (Hebrews 9:14)
For [there is] one God, and one mediator between God and men, the man Christ Jesus; Who gave himself a ransom for all, to be testified in due time. (1 Timothy 2:5‑6)